Your Questions, Answered

General & Positioning

  • PIMSLS (formerly PMA.studio) is Pathomation’s advanced, fully web-based environment for working with whole slide images (WSI), digital pathology, and virtual microscopy.

    It acts as a customizable cockpit for researchers, imaging scientists and histopathologists, allowing users to configure their workflow on the fly with adjustable panels which contain robust tools.  

  • PIMSLS is built for: 

    • Research pathologists 

    • Imaging scientists 

    • Bioinformaticians  

    • AI developers 

    • CROs, pharma, biotech & academic research teams 

    It supports workflows ranging from annotation, quantitative image analysis, long-distance conferencing, case organization, to AI-assisted research. 

  • PIMSLS is unique because it is: 

    • Fully customizable: Users can rearrange panels, workflows, ribbons, and layouts. 

    • Interoperable: Works with 

    • all kinds of network enabled storage 

    • third party analysis tools including HALO & Visiopharm 

    • third party AI tools to order and view analyses 

    • the rest of the Pathomation ecosystem including PMA.core, PMA.start & My Pathomation. 

    • Modular and extensible: Integrated annotation tools, conferencing, forms, server connectivity, automation APIs, and AI workflows. 

    • Future-ready: Built to integrate with heterogeneous data sources and advanced computational pathology pipelines. 

Research workflows & Customization

  • Users can configure: 

    • Panels (annotations, browser, tray, search, forms, info, bookmarks…) 

    • Ribbon layouts 

    • Panel stacks and interface layouts 

    • Viewport components (overview, scale bar, barcode, zoom control, slide label) 

    • Server connectivity 

    • Shared links & permissions 

    • Custom actions via scripting and the PIMS LS API  

    This allows each research group to tailor PIMS LS to its own workflow. 

  • Users can change: 

    • Grid layouts 

    • Viewport numbers 

    • Tab-based views 

    • Floating vs. docked panels 

    Administrators can define default layouts for entire teams or studies.  

  • PIMSLS plugs directly into your storage drive(s), so images and cases can be browsed in the same way you would access them on your file explorer. 

    There are also two extra ways to further organize and filter your slides: 

    1. You can add metadata using Forms, and search or filter cases and slides based on those form values in the Search panel 

    2. The Virtual Tray allows users to group slides, annotate metadata, organize cases, and display slide information such as dimensions, channels, barcodes, and forms. It works like a digital version of the pathologist’s physical slide tray. 

  • Yes. Users can: 

    • Bookmark slides & ROIs 

    • Search & filter by form metadata, barcode, filename, classification 

    • Quickly navigate large datasets or folders 

Image types, Storage & Interoperability

  • PIMSLS connects to virtually any storage location including: 

    • Network drives 

    • Azure 

    • AWS S3 

    • FTP sources  

    This makes it ideal for distributed research environments, multi-site collaboration, and large-scale datasets. 

    All Pathomation products support all major file formats. You can see the full list here.

  • Yes. 

    • PMA.start connects local images directly to the PIMS LS environment 

    This allows hybrid workflows across desktop, cloud, and server environments.  

Annotations & Quantitative Analysis

  • PIMSLS includes one of the most extensive annotation modules in digital pathology. Tools include: 

    • Simple shapes: points, circles, rectangles, lines 

    • Polygon tools: standard polygon, freehand, closed freehand, compound freehand 

    • Multipoint counting tools  

    All measurements and annotations are CE-IVD certified for diagnostic measurement of distances and areas. 

    Import/export formats include WKT, Visiopharm MLD, HALO XML, Definiens/Aperio XML, and CSV.  

  • Yes. PIMSLS supports: 

    • Import: HALO, Visiopharm, Aperio/Definiens XML, CSV, WKT 

    • Export: HALO, Visiopharm, Aperio/Definiens XML, CSV, WKT 

    This allows seamless integration with analysis of pipelines, CRO reporting, and algorithm development.  

AI and Computational Pathology

  • Yes. PIMSLS includes a built-in AI Analysis module allowing users to: 

    • Run algorithms on a region of interest (ROI), entire slide, or viewport 

    • View results with overlays 

    • Navigate detected features 

    • Validate dimensions to ensure the ROI fits the algorithm’s requirements 

    • Review detailed success/error logs  

    This is extremely useful for research pipelines, pre-clinical studies, biomarker quantification, and AI validation. 

Collaboration & Conferencing

  • PIMSLS supports advanced collaboration through: 

    • Virtual conferences with real-time synchronized on-slide navigation & annotation 

    • Shared links (view-only or full-access) 

    • Custom share options: password protection, expiring links, QR code access 

    • Case- or folder-based sharing for teaching, research, or reviews 

    • Long-distance slide seminars  

    This makes it ideal for teaching, tumor boards, research groups, and remote collaboration. 

  • PIMS For Life Sciences offers: 

    • Multi-user synchronized navigation 

    • Secure password-protected sessions 

    • Joint or leader-only on-slide drawn or written annotations 

    • Grid view for multiple-slide discussion 

    • Long-distance teaching capabilities (ideal for courses, pathology training, biomarker review)  

  • Yes. PIMSLS is built for high-performance environments with: 

    • Multiple parallel PMA.core connections 

    • Large-scale WSI dataset compatibility with 70+ file types supported (see pathomation.com/formats ) across brightfield, fluorescence and z-stacking 

    • Metadata integration 

    • Advanced annotation & AI modules 

    • Role-based permissions for multi-user teams 

    • Extensive configurability 

    It is used by universities, pharma, AI developers, and biotech companies globally.

  • Yes. PIMSLS exposes automation endpoints for: 

    • Creating share links 

    • Loading slides programmatically 

    • Integrating into LIMS/LIS/PACS/ELN systems 

    • Triggering custom workflows 

    • Accessing version info and server metadata  

    This makes it easy to embed PIMS LS into enterprise research pipelines and AI development workflows. 

  • Administrators can monitor: 

    • User access 

    • Server visits (IP, device, success/failure) 

    • Shared content overview 

    • System logs (including ELMAH logs) 

    • Ribbon & panel defaults 

    • PMA.core server status and ordering  

Enterprise, Automation & APIs

  • Yes, PIMSLS contributes significantly to sustainable research and pathology operations: 

    1. Reduced physicallogistics

    • Decreases microscope use, printed photos, glass slide transportation, and storage needs 

    • Reduces carbon footprint of inter-lab shipping 

    1. Supports remote work

    • Enables cross-site collaboration without travel 

    • Reduces commuting emissions for researchers and trainees 

    1. Extends the lifecycle of digital assets

    • Slides can be re-used, organized, shared, and analyzed indefinitely without re-scanning 

    • Supports long-term research sustainability and reproducibility 

    1. Efficient infrastructure usage

    • Works with existing servers, cloud systems, and local devices 

    • Reduces redundant data storage through barcode & metadata mapping 

Sustainable & responsible Research

Education & Training Use

  • Yes, PIMSLS is frequently used for: 

    • Digital pathology course content in Hospitals and Universities 

    • Collaborative learning sessions 

    • Quizzes and guided slide exploration 

    • External sharing links for students (with expiration)